Richard Pariza

CAREER SUMMARY

Richard Pariza received his Ph.D. degree in Organic Chemistry from Purdue University. He has more than 30 years of leadership on major projects in the pharmaceutical industry. His experience includes Discovery and Development research, management or executive positions with Abbott Laboratories, Protarga, Natural Pharmaceuticals, OncQuest, and Cedarburg Hauser Pharmaceuticals. He has broad knowledge of API suppliers, auditing for safety and cGMP compliance and manufacturing competence. His specialty is designing and improving the processes to make new drugs. He is a former founding editor and now member of the Editorial Board of Organic Process Research & Development, a peer-reviewed Journal from the American Chemical Society, which publishes state-of-the-art manufacturing research from all major pharmaceutical companies. He also has an appointment as a Visiting Research Assistant Professor at the University of Illinois at Chicago.

KEY ACCOMPLISHMENTS

  • More than 30 years leadership in the pharmaceutical and chemical industry
  • Prominent Scientist, discovering new compounds and chemical processes
  • Passionate Mentor, providing scientific leadership and encouraging professional growth, publications and patents
  • Enthusiastic Lecturer, delivering numerous scientific and business development presentations, chairing sessions and organizing conferences worldwide
  • Expertise in the chemistry of Vitamin D and analogs, antiinfectives (macrolides, quinolones, HIV protease inhibitors), taxanes, petidomimetics, and other anticancer drugs, steroids, prostaglandins, and cannabinoids
  • Chairman of the Organizing Committee for the 20th IUPAC Symposium on the Chemistry of Natural Products (Chicago, 1996)
  • Elected Chairman of the 1995 Gordon Research Conference on Organic Reactions and Processes
  • Former Associate Editor of Organic Process Research & Development; an American Chemical Society scholarly publication; currently a member of the Editorial Board
  • Member of the American Chemical Society, Organic, Medicinal and Physical Sections; Chicago and Milwaukee Local Sections

PROFESSIONAL EXPERIENCE

Visiting Research Assistant Professor in the Department of Chemistry, University of Illinois-Chicago (August 2009 - Present) Works with graduate students in the laboratory of Professor Robert Moriarty to develop new chemical technology.

Cedarburg Pharmaceuticals, Grafton, WI (2003 - Present)
Vice President, R&D (2003-2006)
Chief Scientific Officer (April 2006 – Present)
Supports the Company in developing creative approaches to solving the customer's synthetic challenges and scale-up problems using a scientific understanding of mechanisms and manufacturing processes; responsibilities include, but are not limited to, literature searching, designing experiments, providing scientific leadership to Process Development chemists, writing patent applications and scientific publications, attending and making presentations at scientific conferences. The CSO has market development responsibilities: reviewing proposals and making presentations to customers.

Natural Pharmaceuticals, Inc. Beverly, MA (July 2001 to 2003)
Senior Research Advisor, Process Chemistry and Intellectual Property

  • Establishing the patent portfolio and conducting research on the chemical processes for NPI, especially semisynthetic paclitaxel.

Protarga, Inc., King of Prussia, PA (12/99 – 6/01)
VP Chemistry, Manufacturing and Process Research

  • Finding and qualifying drug substance and drug product manufacturers. Placing orders, overseeing the QA audits.
  • Creating and directing the manufacturing budgets and schedules.
  • Supervising the preparation of documentation for regulatory filings.
  • Recruiting, hiring and managing the synthetic and analytical chemists for process research, analytical methods development, technology transfer and vendor audit functions.
  • Member of Senior Management Team

CP Consulting, Inc., Zion, IL (1995 – 1999)
Consultant

  • Technical consultant to the Chemical Sciences Division of G.D. Searle and other pharmaceutical companies.
  • Regularly participated in technical meetings and trade shows.
  • Consulted on chemical, business and marketing issues.
  • Helped design several laboratories, including a state-of-the-art cGMP final product isolation laboratory that also accommodates hazardous materials and is used for the manufacturing of a highly potent commercial drug.

Abbott Laboratories Chemical and Agricultural Products Div, North Chicago, IL (1989 – 1995)
Department Manager Process Research

  • Created the Process Chemistry Research Department in the Chemical Products Division, reporting to V.P. Chemical R&D and Manufacturing.
  • Recruited and hired a superior professional staff that won nearly all the divisional scientific awards each year. Built the Department to 50 chemists and engineers. Provided scientific leadership and mentoring, encouraged the writing of publications and patents.
  • Responsible for synthesizing all clinical bulk drugs for new pharmaceutical candidates from medicinal discovery, developing efficient cost-effective processes, validating the new processes and moving them to large manufacturing scale when clinically viable.
  • Supervised the writing of research reports, batch records and FDA CMC documentation, working closely with analytical and formulations groups.
  • Negotiated budgets and schedules with top R&D management, assigned process groups, coordinated analytical support for the pilot plant time and consultants, developed raw material sources, technology transfer and vendor supply strategies.
  • Worked closely with the "Customer Teams" to assure their satisfaction. Met or exceeded incentive goals.
  • Annual budgets as high as $20 Million.
  • Served on committees to design several laboratory buildings: Scale-up laboratories and R9, a $40 Million state-of-the-art GMP pilot plant.
  • Part of the Divisional incentive bonus plan; received incentive stock options.

Pharmaceutical Products Division, Abbott Park, IL (1983 – 1989)
Department Manager, Process Research

  • Established and built the first Process Chemistry Department in Abbott's Pharmaceutical Division.
  • Recruited and hired the professional staff of 15 chemists.
  • Designed and equipped two laboratory modules and a kilo scale laboratory.
  • Provided medicinal chemists with larger supplies of key intermediates, high-pressures hydrogenations and practical scale-up chemistry.
  • Hands-on laboratory work included a new synthesis of a cardiovascular drug and pioneering new chemistry that produced leads for the anti-infective discovery and anti-viral discovery projects. Several patents resulted.
  • Received incentive stock options.

EDUCATION

Purdue University, West Lafayette, IN.
Ph.D. Organic Chemistry (1985)
Synthetic Organic Chemistry (Prof. P. L. Fuchs)
Analytical Chemistry minor.

University of Wisconsin-Milwaukee, Milwaukee, WI.
B.S. Chemistry

PUBLICATIONS, PRESENTATIONS, AND PATENTS

  • More than twenty-five scientific publications in peer-reviewed journals.
  • Two technical book chapters and several published marketing interviews.
  • Eleven invited presentations at major scientific conferences; fifteen invited presentations at Universities and Institutes.
  • Ten issued US patents; several other patents pending, some with foreign issue.